- The removal of oxygen atoms or molecules from a material
Deoxygenation is a chemical reaction involving the removal of molecular oxygen (O2) from a reaction mixture or solvent, or the removal of oxygen atoms from a molecule.
Classic representatives of deoxygenation are:
A chemical reagent for the deoxygenation of many sulfur and nitrogen oxo compounds is the trifluoroacetic anhydride / sodium iodide combination for example in the deoxygenation of the sulfoxide diphenylsulfoxide to the sulfide diphenylsulfide:
The reaction mechanism is based on activation of the sulfoxide by a trifluoroacetyl group and oxidation of iodine. Iodine is formed quantitatively in this reaction and therefore the reagent is used for the analytical detection of many oxo compounds.